PGT-A
PGT-A is a genetic screening test for embryos created through in vitro fertilisation. It assesses the number of chromosomes in the analysed cells and provides additional information when selecting an embryo for transfer.
The biopsy is performed by an embryologist in the laboratory, and the sample is analysed in a specialised genetics laboratory. No additional procedure, anaesthesia or recovery is required for the patient.
At Adella Clinic, we will explain the possible results, how they are interpreted and how they may influence the embryo transfer plan.
The biopsy is performed by an embryologist in the laboratory, and the sample is analysed in a specialised genetics laboratory. No additional procedure, anaesthesia or recovery is required for the patient.
At Adella Clinic, we will explain the possible results, how they are interpreted and how they may influence the embryo transfer plan.
Duration
The test is performed once suitable embryos have reached the blastocyst stage and requires time for genetic analysis.
Stay at the Clinic
No additional stay is required beyond the visits associated with the IVF procedure.
Feeling
The biopsy is performed on the embryos in the laboratory and does not cause physical discomfort for the patient.
Additional Information When Selecting an Embryo for Transfer
What information does PGT-A provide?
What does it mean?
- PGT-A stands for preimplantation genetic testing for aneuploidy.
- The test assesses whether the analysed cells contain the expected number of chromosomes.
- An embryo with the expected number of chromosomes is classified as euploid.
What is important to know?
- An extra or missing chromosome is classified as aneuploidy.
- Chromosomal abnormalities may affect implantation and the development of a pregnancy.
- The result may be euploid, aneuploid, mosaic or inconclusive
Individual Assessment Based on Medical History
When can PGT-A be discussed?
-
1
At a more advanced reproductive age
As oocyte age increases, the likelihood that some embryos will have chromosomal abnormalities also increases.
PGT-A may be discussed when several blastocysts are expected to be obtained and the result could help inform embryo selection for transfer. -
2
Following recurrent pregnancy loss
Chromosomal abnormalities are among the possible causes of early pregnancy loss.
PGT-A may form part of a broader assessment, but it does not replace other investigations aimed at identifying the cause. -
3
Following unsuccessful embryo transfers
After several transfers without implantation, the test may provide additional information about the embryos.
Before making a recommendation, we also assess the uterine cavity, the endometrium, the developmental stage of the embryos and other factors. -
4
When there are several embryos to choose from
PGT-A may help with the selection of a single embryo for transfer when several suitable blastocysts have been obtained.
The potential benefit is always considered in relation to the number of embryos available.
